GP surgeries and pharmacies will be closed for four days at Christmas, from December 24-27, and for another four days at New Year between December 31 - January 3.
Residents are being urged to be aware of the changes, re-stock their medicine cabinets and plan ahead for repeat prescriptions.
Dr George Crooks, medical director of NHS 24, said: “There will be two four-day closures this year, so it is essential that everyone is prepared and knows when their local services are available.
“If you are unlucky enough to get a cough, cold or flu, buying over the counter medicine, staying at home and keeping warm will make you feel much better.
“If your symptoms worsen, you should seek a routine doctor’s appointment or contact NHS 24.”